Tails of Intrigue

Tails of Intrigue Phosphorylation of RNA Polymerase II Mediates Histone Methylation

Histone lysine methylation plays a key role in the organization of chromatin structure and the regulation of gene expression. Recent studies demonstrated that the yeast Set1 and Set2 histone methyltransferases are recruited to mRNA coding regions by the PAF transcription elongation complex in a manner dependent upon the phosphorylation state of the carboxy-terminal domain of RNA polymerase II. ...

Capturing plant intrigue

electron micrographs of many plant features and details of their reproduction. “Our work results from an enthusiasm to communicate and express our shared passion and fascination for the beauty of sexual reproduction among flowering plants,” the authors write. Their aim is to engage audiences for the research and conservation work in the plant sciences carried out throughout the world. And they ...

Intrigue at the immune synapse.

Gastric Trichobezoar: An Enduring Intrigue

Trichobezoar is a rare condition that may pose a diagnostic challenge. Patients with this condition often have an underlying psychiatric illness, and history may not be easily forthcoming. The condition should be entertained especially in young females. Delay in diagnosis may lead to futile complications. We report a classic case of trichobezoar in terms of patient profile, presentation, and in...

Anodal Stimulation - The Intrigue Continues

When cardiac pacing is performed in the bipolar configuration, both the cathode (negatively charged electrode) and the anode (positively charged electrode) are in contact with the myocardium. Myocardial stimulation by the pacing stimulus typically occurs only at the interface with the cathode. This is because (i) given equal sized electrodes, anodal stimulation has a higher threshold compared t...